@article{bib1,
	author = {Ab-Rahman, HA and Rahim, H and AbuBakar, S and Wong, PF},
	journal = {International Journal of Medical Sciences},
	year = {2016},
	pages = {179--186},
	title = {Macrophage activation {Syndrome}-{Associated} markers in severe dengue},
	volume = {13},
}

@article{bib2,
	author = {Barto{\' n}, K},
	year = {2020},
	title = {MuMIn: Multi-{Model} {Inference}},
	howpublished = {https://CRAN.R-project.org/package=MuMIn},
}

@article{bib3,
	author = {Brasier, AR and Ju, H and Garcia, J and Spratt, HM and Victor, SS and Forshey, BM and Halsey, ES and Comach, G and Sierra, G and Blair, PJ and Rocha, C and Morrison, AC and Scott, TW and Bazan, I and Kochel, TJ and {Venezuelan Dengue Fever Working Group}},
	journal = {The American Journal of Tropical Medicine and Hygiene},
	year = {2012},
	pages = {341--348},
	title = {A three-component biomarker panel for prediction of dengue hemorrhagic fever},
	volume = {86},
}

@article{bib4,
	author = {Cattarino, L and Rodriguez-Barraquer, I and Imai, N and Cummings, DAT and Ferguson, NM},
	journal = {Science Translational Medicine},
	year = {2020},
	title = {Mapping global variation in dengue transmission intensity},
	volume = {12},
}

@article{bib5,
	author = {Conroy, AL and G{\' e}lvez, M and Hawkes, M and Rajwans, N and Tran, V and Liles, WC and Villar-Centeno, LA and Kain, KC},
	journal = {International Journal of Infectious Diseases},
	year = {2015},
	pages = {45--53},
	title = {Host biomarkers are associated with progression to dengue haemorrhagic fever: a nested case-control study},
	volume = {40},
}

@article{bib6,
	author = {Finkelstein, JL and Colt, S and Layden, AJ and Krisher, JT and Stewart-Ibarra, AM and Polhemus, M and Beltr{\' a}n-Ayala, E and Tedesco, JM and C{\' a}rdenas, WB and Endy, T and Mehta, S},
	journal = {The Journal of Infectious Diseases},
	year = {2020},
	pages = {91--101},
	title = {Micronutrients, immunological parameters, and dengue virus infection in coastal {Ecuador}: a nested {Case}-{Control} study in an infectious disease surveillance program},
	volume = {221},
}

@article{bib7,
	author = {Han, L and Ao, X and Lin, S and Guan, S and Zheng, L and Han, X and Ye, H},
	journal = {Frontiers in Microbiology},
	year = {2019},
	title = {Quantitative comparative proteomics reveal biomarkers for dengue disease severity},
	volume = {10},
}

@article{bib8,
	author = {Harrell Jr, FE},
	year = {2019},
	title = {rms: Regression {Modeling} {Strategies}},
	howpublished = {https://CRAN.R-project.org/package=rms},
}

@article{bib9,
	author = {Hastie, T and Tibshirani, R and Tibshirani, RJ},
	journal = {arXiv},
	year = {2017},
	title = {Extended comparisons of best subset selection, forward stepwise selection, and the lasso},
	howpublished = {https://arxiv.org/abs/1707.08692},
}

@article{bib10,
	author = {Heinze, G and Wallisch, C and Dunkler, D},
	journal = {Biometrical Journal},
	year = {2018},
	pages = {431--449},
	title = {Variable selection - {A} review and recommendations for the practicing statistician},
	volume = {60},
}

@article{bib11,
	author = {Hocking, RR and Leslie, RN},
	journal = {Technometrics},
	year = {1967},
	pages = {531--540},
	title = {Selection of the best subset in regression analysis},
	volume = {9},
}

@article{bib12,
	author = {Jaenisch, T and Tam, DT and Kieu, NT and Van Ngoc, T and Nam, NT and Van Kinh, N and Yacoub, S and Chanpheaktra, N and Kumar, V and See, LL and Sathar, J and Sandoval, EP and Alfaro, GM and Laksono, IS and Mahendradhata, Y and Sarker, M and Ahmed, F and Caprara, A and Benevides, BS and Marques, ET and Magalhaes, T and Brasil, P and Netto, M and Tami, A and Bethencourt, SE and Guzman, M and Simmons, C and Quyen, NT and Merson, L and Dung, NT and Beck, D and Wirths, M and Wolbers, M and Lam, PK and Rosenberger, K and Wills, B},
	journal = {BMC Infectious Diseases},
	year = {2016},
	title = {Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries},
	volume = {16},
}

@article{bib13,
	author = {John, DV and Lin, YS and Perng, GC},
	journal = {Journal of Biomedical Science},
	year = {2015},
	title = {Biomarkers of severe dengue disease - a review},
	volume = {22},
}

@article{bib14,
	author = {Ju, H and Brasier, AR},
	journal = {BMC Research Notes},
	year = {2013},
	title = {Variable selection methods for developing a biomarker panel for prediction of dengue hemorrhagic fever},
	volume = {6},
}

@article{bib15,
	author = {Katzelnick, LC and Gresh, L and Halloran, ME and Mercado, JC and Kuan, G and Gordon, A and Balmaseda, A and Harris, E},
	journal = {Science},
	year = {2017},
	pages = {929--932},
	title = {Antibody-dependent enhancement of severe dengue disease in humans},
	volume = {358},
}

@article{bib16,
	author = {Lee, YH and Leong, WY and Wilder-Smith, A},
	journal = {Journal of General Virology},
	year = {2016},
	pages = {3103--3119},
	title = {Markers of dengue severity: a systematic review of cytokines and chemokines},
	volume = {97},
}

@article{bib17,
	author = {Mapalagamage, M and Handunnetti, SM and Wickremasinghe, AR and Premawansa, G and Thillainathan, S and Fernando, T and Kanapathippillai, K and De Silva, AD and Premawansa, S},
	journal = {Journal of Clinical Microbiology},
	year = {2020},
	title = {High levels of serum angiopoietin 2 and angiopoietin 2/1 ratio at the critical stage of dengue hemorrhagic fever in patients and association with clinical and biochemical parameters},
	volume = {58},
}

@article{bib18,
	author = {McBride, A and Khanh Lam, P},
	journal = {Frontiers of Medicine},
	year = {2020},
	title = {Visual and biochemical evidence of glycocalyx disruption in human dengue infection, and association with plasma leakage severity},
	volume = {7},
}

@article{bib19,
	author = {Midgley, CM and Bajwa-Joseph, M and Vasanawathana, S and Limpitikul, W and Wills, B and Flanagan, A and Waiyaiya, E and Tran, HB and Cowper, AE and Chotiyarnwong, P and Chotiyarnwon, P and Grimes, JM and Yoksan, S and Malasit, P and Simmons, CP and Mongkolsapaya, J and Screaton, GR},
	journal = {Journal of Virology},
	year = {2011},
	pages = {410--421},
	title = {An in-depth analysis of original antigenic sin in dengue virus infection},
	volume = {85},
}

@article{bib20,
	author = {Modhiran, N and Watterson, D and Muller, DA and Panetta, AK and Sester, DP and Liu, L and Hume, DA and Stacey, KJ and Young, PR},
	journal = {Science Translational Medicine},
	year = {2015},
	title = {Dengue virus {NS1} protein activates cells via {Toll}-like receptor 4 and disrupts endothelial cell monolayer integrity},
	volume = {7},
}

@article{bib21,
	author = {Morra, ME and Altibi, AMA and Iqtadar, S and Minh, LHN and Elawady, SS and Hallab, A and Elshafay, A and Omer, OA and Iraqi, A and Adhikari, P and Labib, JH and Elhusseiny, KM and Elgebaly, A and Yacoub, S and Huong, LTM and Hirayama, K and Huy, NT},
	journal = {Reviews in Medical Virology},
	year = {2018},
	title = {Definitions for warning signs and signs of severe dengue according to the {WHO} 2009 classification: systematic review of literature},
	volume = {28},
}

@article{bib22,
	author = {Mukherjee, S and Tripathi, A},
	journal = {Medical Microbiology and Immunology},
	year = {2020},
	pages = {631--640},
	title = {Association of serum {C}-reactive protein level and polymorphisms with susceptibility to dengue infection and severe clinical outcome among eastern indian patients},
	volume = {209},
}

@article{bib23,
	author = {Oliveira, R and Cordeiro, MT and Moura, P and Baptista Filho, PNB and Braga-Neto, UM and Marques, ETA and Gil, L},
	journal = {Journal of Clinical Virology},
	year = {2017},
	pages = {39--45},
	title = {Serum cytokine/chemokine profiles in patients with dengue fever ({DF}) and dengue hemorrhagic fever ({FHD}) by using protein array},
	volume = {89},
}

@article{bib24,
	author = {Pandey, N and Jain, A and Garg, RK and Kumar, R and Agrawal, OP and Lakshmana Rao, PV},
	journal = {Archives of Virology},
	year = {2015},
	pages = {1463--1475},
	title = {Serum levels of {IL}-8, {IFN}\gamma{}, {IL}-10, and {TGF} \beta{} and their gene expression levels in severe and non-severe cases of dengue virus infection},
	volume = {160},
}

@article{bib25,
	author = {Pang, J and Lindblom, A and Tolfvenstam, T and Thein, TL and Naim, AN and Ling, L and Chow, A and Chen, MI and Ooi, EE and Leo, YS and Hibberd, ML},
	journal = {PLOS ONE},
	year = {2016},
	title = {Discovery and validation of prognostic biomarker models to guide triage among adult dengue patients at early infection},
	volume = {11},
}

@article{bib26,
	author = {Piironen, J and Vehtari, A},
	journal = {Statistics and Computing},
	year = {2017},
	pages = {711--735},
	title = {Comparison of bayesian predictive methods for model selection},
	volume = {27},
}

@article{bib27,
	author = {Puerta-Guardo, H and Glasner, DR and Espinosa, DA and Biering, SB and Patana, M and Ratnasiri, K and Wang, C and Beatty, PR and Harris, E},
	journal = {Cell Reports},
	year = {2019},
	pages = {1598--1613},
	title = {Flavivirus {NS1} triggers {Tissue}-{Specific} vascular endothelial dysfunction reflecting disease tropism},
	volume = {26},
}

@article{bib28,
	address = {Vienna, Austria},
	author = {{R Core Development Team}},
	year = {2020},
	publisher = {R Foundation for Statistical Computing},
	title = {A language and environment for statistical computing},
}

@article{bib29,
	author = {Rathakrishnan, A and Wang, SM and Hu, Y and Khan, AM and Ponnampalavanar, S and Lum, LC and Manikam, R and Sekaran, SD},
	journal = {PLOS ONE},
	year = {2012},
	title = {Cytokine expression profile of dengue patients at different phases of illness},
	volume = {7},
}

@article{bib30,
	author = {Rathore, AP and Farouk, FS and St John, AL},
	journal = {Current Opinion in Virology},
	year = {2020},
	pages = {1--8},
	title = {Risk factors and biomarkers of severe dengue},
	volume = {43},
}

@article{bib31,
	author = {Redoni, M and Yacoub, S and Rivino, L and Giacobbe, DR and Luzzati, R and Di Bella, S},
	journal = {Reviews in Medical Virology},
	year = {2020},
	title = {Dengue: Status of current and under-development vaccines},
	volume = {30},
}

@article{bib32,
	author = {Robinson, M and Einav, S},
	journal = {Trends in Microbiology},
	year = {2020},
	pages = {478--486},
	title = {Towards {Predicting} {Progression} to {Severe} {Dengue}},
	volume = {28},
}

@article{bib33,
	author = {Rodriguez-Manzano, J and Chia, PY and Yeo, TW and Holmes, A and Georgiou, P and Yacoub, S},
	journal = {Current Infectious Disease Reports},
	year = {2018},
	title = {Improving {Dengue} {Diagnostics} and {Management} {Through} {Innovative} {Technology}},
	volume = {20},
}

@article{bib34,
	author = {S S, SG and Pillai, AB and Ramachandrappa, VS and Kadhiravan, T and Dhodapkar, R and Kah, J and Rajendiran, S},
	journal = {Journal of Clinical Virology : The Official Publication of the Pan American Society for Clinical Virology},
	year = {2017},
	pages = {62--67},
	title = {Increased serum levels of macrophage activation marker {sCD163} in dengue patients},
	volume = {86},
}

@article{bib35,
	author = {Sauerbrei, W and Perperoglou, A and Schmid, M and Abrahamowicz, M and Becher, H and Binder, H and Dunkler, D and Harrell, FE and Royston, P and Heinze, G and {for TG2 of the STRATOS initiative}},
	journal = {Diagnostic and Prognostic Research},
	year = {2020},
	title = {State of the art in selection of variables and functional forms in multivariable analysis-outstanding issues},
	volume = {4},
}

@article{bib36,
	author = {Schifano, ED},
	journal = {Communications for Statistical Applications and Methods},
	year = {2019},
	pages = {103--129},
	title = {A review of analysis methods for secondary outcomes in case-control studies},
	volume = {26},
}

@article{bib37,
	author = {Screaton, G and Mongkolsapaya, J and Yacoub, S and Roberts, C},
	journal = {Nature Reviews Immunology},
	year = {2015},
	pages = {745--759},
	title = {New insights into the immunopathology and control of dengue virus infection},
	volume = {15},
}

@article{bib38,
	author = {Soo, KM and Khalid, B and Ching, SM and Tham, CL and Basir, R and Chee, HY},
	journal = {PeerJ},
	year = {2017},
	title = {Meta-analysis of biomarkers for severe dengue infections},
	volume = {5},
}

@article{bib39,
	author = {Soundravally, R and Agieshkumar, B and Daisy, M and Sherin, J and Cleetus, CC},
	journal = {Infection},
	year = {2015},
	pages = {13--19},
	title = {Ferritin levels predict severe dengue},
	volume = {43},
}

@article{bib40,
	author = {St John, AL and Rathore, AP and Raghavan, B and Ng, ML and Abraham, SN},
	journal = {eLife},
	year = {2013},
	title = {Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage},
	volume = {2},
}

@article{bib41,
	author = {Suwarto, S and Sasmono, RT and Sinto, R and Ibrahim, E and Suryamin, M},
	journal = {The Journal of Infectious Diseases},
	year = {2017},
	pages = {992--999},
	title = {Association of endothelial glycocalyx and tight and adherens junctions with severity of plasma leakage in dengue infection},
	volume = {215},
}

@article{bib42,
	author = {Tchetgen Tchetgen, EJ},
	journal = {Biostatistics},
	year = {2014},
	pages = {117--128},
	title = {A general regression framework for a secondary outcome in case-control studies},
	volume = {15},
}

@article{bib43,
	author = {Tomashek, KM and Wills, B and See Lum, LC and Thomas, L and Durbin, A and Leo, YS and de Bosch, N and Rojas, E and Hendrickx, K and Erpicum, M and Agulto, L and Jaenisch, T and Tissera, H and Suntarattiwong, P and Collers, BA and Wallace, D and Schmidt, AC and Precioso, A and Narvaez, F and Thomas, SJ and Edelman, R and Siqueira, JB and Cassetti, MC and Dempsey, W and Gubler, DJ},
	journal = {PLOS Neglected Tropical Diseases},
	year = {2018},
	title = {Development of standard clinical endpoints for use in dengue interventional trials},
	volume = {12},
}

@article{bib44,
	author = {Vasey, B and Shankar, AH and Herrera, BB and Becerra, A and Xhaja, K and Echenagucia, M and Machado, SR and Caicedo, D and Miller, J and Amedeo, P and Naumova, EN and Bosch, I and {Norma Blumenfeld deBosch}},
	journal = {PLOS Neglected Tropical Diseases},
	year = {2020},
	title = {Multivariate time-series analysis of biomarkers from a dengue cohort offers new approaches for diagnosis and prognosis},
	volume = {14},
}

@article{bib45,
	author = {Vuong, NL and Le Duyen, HT and Lam, PK and Tam, DTH and Vinh Chau, NV and Van Kinh, N and Chanpheaktra, N and Lum, LCS and Pleit{\' e}s, E and Jones, NK and Simmons, CP and Rosenberger, K and Jaenisch, T and Halleux, C and Olliaro, PL and Wills, B and Yacoub, S},
	journal = {BMC Medicine},
	year = {2020},
	title = {C-reactive protein as a potential biomarker for disease progression in dengue: a multi-country observational study},
	volume = {18},
}

@article{bib46,
	author = {Vuong, NL and Quyen, NTH and Tien, NTH and Tuan, NM and Kien, DTH and Lam, PK and Tam, DTH and Van Ngoc, T and Yacoub, S and Jaenisch, T and Geskus, RB and Simmons, CP and Wills, BA},
	journal = {Clinical Infectious Diseases},
	year = {2021},
	title = {Higher plasma viremia in the febrile phase is associated with adverse dengue outcomes irrespective of infecting serotype or host immune status: an analysis of 5642 vietnamese cases},
	volume = {72},
}

@article{bib47,
	author = {Vuong, NL},
	year = {2021},
	title = {eLife\textunderscore{}{Biomarkers}\textunderscore{}{Dengue}\textunderscore{}2021},
	howpublished = {https://archive.softwareheritage.org/swh:1:dir:2208b3484f7b7568f4ecde57bb8f0f641194a6b0;origin=https://github.com/Nguyenlamvuong/eLife\textunderscore{}Biomarkers\textunderscore{}Dengue\textunderscore{}2021;visit=swh:1:snp:531311172177ecad060ca11b9c3752edb33ce261;anchor=swh:1:rev:847d8e0f564eeb3f075b443205fb3384598bc2b4},
}

@article{bib48,
	author = {Whitehorn, J and Yacoub, S},
	journal = {Clinical Medicine},
	year = {2019},
	pages = {149--152},
	title = {Global warming and arboviral infections},
	volume = {19},
}

@article{bib49,
	author = {Wickham, H},
	year = {2016},
	publisher = {Springer-Verlag},
	title = {Ggplot2: Elegant {Graphics} for {Data} {Analysis}},
}

@article{bib50,
	author = {{World Health Organization}},
	year = {2019},
	title = {Strong country capacity, improved tools and community engagement critical to enhancing dengue prevention and control},
	howpublished = {https://www.who.int/news/item/14-11-2019-strong-country-capacity-improved-tools-and-community-engagement-critical-to-enhancing-dengue-prevention-and-control},
}

@article{bib51,
	author = {{World Health Organization}},
	year = {2020},
	title = {Dengue and severe dengue},
	howpublished = {https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue},
}

@article{bib52,
	author = {Yacoub, S and Kotit, S and Yacoub, MH},
	journal = {Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences},
	year = {2011},
	pages = {1719--1729},
	title = {Disease appearance and evolution against a background of climate change and reduced resources},
	volume = {369},
}

@article{bib53,
	author = {Yacoub, S and Lam, PK and Vu, LHM and Le, TL and Ha, NT and Toan, TT and Van, NT and Quyen, NTH and Le Duyen, HT and Van Kinh, N and Fox, A and Mongkolspaya, J and Wolbers, M and Simmons, CP and Screaton, GR and Wertheim, H and Wills, B},
	journal = {Journal of Infectious Diseases},
	year = {2016},
	pages = {697--706},
	title = {Association of microvascular function and endothelial biomarkers with clinical outcome in dengue: an observational study},
	volume = {214},
}

@article{bib54,
	author = {Yacoub, S and Mongkolsapaya, J and Screaton, G},
	journal = {F1000Research},
	year = {2016},
	title = {Recent advances in understanding dengue},
	volume = {5},
}

@article{bib55,
	author = {Yacoub, S and Lam, PK and Huynh, TT and Nguyen Ho, HH and Dong Thi, HT and Van, NT and Lien, LT and Ha, QNT and Le, DHT and Mongkolspaya, J and Culshaw, A and Yeo, TW and Wertheim, H and Simmons, C and Screaton, G and Wills, B},
	journal = {Clinical Infectious Diseases},
	year = {2017},
	pages = {1453--1461},
	title = {Endothelial nitric oxide pathways in the pathophysiology of dengue: a prospective observational study},
	volume = {65},
}

@article{bib56,
	author = {Yong, YK and Tan, HY and Jen, SH and Shankar, EM and Natkunam, SK and Sathar, J and Manikam, R and Sekaran, SD},
	journal = {Journal of Translational Medicine},
	year = {2017},
	title = {Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease},
	volume = {15},
}